Endeavors to Study and Advance Cancer Therapeutics with the Framework of “NanoScience” Research Cluster

Endeavors to Study and Advance Cancer Therapeutics with the Framework of “NanoScience” Research Cluster

13 September, 2020

Several virtual meetings via Videoconference between German – Palestinian researchers was held in July-August 2020 for Nanoscience research cluster.
The "NanoScience” comprises five main research topics:

  1. Exosomes in medical applications
  2. Lipid nanoparticles in cancer therapy
  3. Nanoparticles in agricultural applications
  4. Magnetic nanoparticles in cancer therapy
  5. Carbon nanotubes in neuronal networks

Three main topics: Exosomes in medical applications, Lipid nanoparticles in cancer therapy and Magnetic nanoparticles in cancer therapy are allow for emphasis on studying and improving cancer therapies and treatments. Currently, research teams from both the Palestinian and German side are engaged in an effort towards developing specific projects aiming at exploding nanotechnology methods and composites like nanoliposomes, exosomes and magnetic nanoparticles. 

Aiming at improving the pharmacological profile of anticancer agents by enhancing the potency and/or restraining their side effects and in cooperation with Dr. Agnes Csiszar, Dr. Sabrina Disch and Prof. Bernd Hoffmann, Dr. Yousef Najajreh from Al-Quds University is leading an effort to develop a composite of nanoparticulated anticancer agents in fusogenic liposomes. Additionally, the project aims at biophysical characterization of the end nanocomposite of anticancer drug encapsulated in nanoliposomes or magnetic nanoparticles. At the same time Dr. Sawsan Abusharkh is cooperating with Dr. Agnes a project that aims at studying the interaction of fusogenic liposomes with plasma proteins. 

In conjunction with these efforts Dr. Sami Makharza from Hebron University and Dr. Omar Abed from Arab American University are cooperating with Dr. Simon Mortal, Prof Birgit Strodel and Dr. Thorsten Auth form the German side on a project that focuses on developing targeted exosomes for cancer treatment. 

Finally, Dr. Mohyeddin Assali form An-Najah National University is cooperating with Dr. Csiszar and Prof. Hoffmann on improving the pharmacological profile of combretastatin A-4 in treating cancer. 
 

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